白细胞介素-7受体a抗体-抗体-抗体-生物在线
北京索莱宝科技有限公司
白细胞介素-7受体a抗体

白细胞介素-7受体a抗体

商家询价

产品名称: 白细胞介素-7受体a抗体

英文名称: IL-7Ra

产品编号: bs-1540R

产品价格: null

产品产地: 北京

品牌商标: BIOSS

更新时间: 2025-05-07T13:47:23

使用范围: WB=1:100-500,ELISA=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,

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The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID).